Increased leptin concentration in preterm infants of pre-eclamptic mothers

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Increased leptin concentration in preterm infants of pre-eclamptic mothers.

AIM To study the effect of maternal pre-eclampsia on cord plasma leptin concentrations in preterm infants. METHODS Leptin concentration was analysed in cord plasma of 74 preterm infants, gestational age 24 to 32 weeks. Of these, 14 were born to pre-eclamptic mothers, in 10 intrauterine growth retardation (IUGR) was present, and 59 had been exposed antenatally to corticosteroids. RESULTS The...

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Mothers' attitudes to preterm infants.

Bidder, R. T., Crowe, E. A., and Gray, 0. P. (1974). Archives of Disease in Childhood, 49, 766. Mothers' attitudes to preterm infants. Mothers' attitudes to their preterm and term children were examined and compared using the SemanticDifferential and an interview related to the experiences of mothers during pregnancy and after birth. It was postulated that mothers would show more concern for th...

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Increased cystatin C expression in the pre-eclamptic placenta.

Trophoblast invasion is regulated by proteinases and their inhibitors. Cystatin C inhibits cysteine proteinases. The serum concentration of cystatin C is increased in late pregnancy and pre-eclampsia. We aimed to investigate whether the expression of cystatin C is increased in the pre-eclamptic placenta and to investigate the expression pattern of cystatin C mRNA and protein in placental tissue...

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Increased Placental Phospholipid Levels in Pre-Eclamptic Pregnancies

Physiological pregnancy is associated with an increase in lipids from the first to the third trimester. This is a highly regulated response to satisfy energy and membrane demands of the developing fetus. Pregnancy disorders, such as pre-eclampsia, are associated with a dysregulation of lipid metabolism manifesting in increased maternal plasma lipid levels. In fetal placental tissue, only scarce...

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Plasma Leptin Concentrations in Preterm Infants with Retinopathy of Prematurity (ROP)

Intruduction: This study was conducted to determine blood levels of leptin in premature infants with proliferative ROP.Retinopathy of prematurity (ROP) is a postnatal disorder of retinal vessels that develops in the incompletely vascularized retina of preterm infants. This disorder regresses in most patients but can lead to severe visual impairment. There is evidence that leptin stimulates angi...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition

سال: 2000

ISSN: 1359-2998

DOI: 10.1136/fn.83.1.f13